Article
Extracellular calcium (Ca2+o)-sensing receptor in a mouse monocyte-macrophage cell line (J774): potential mediator of the actions of Ca2+o on the function of J774 cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 1998
Yamaguchi T, Kifor O, Chattopadhyay N, Bai M, Brown E M
Abstract excerpt
The calcium-sensing receptor (CaR) is a G protein-coupled receptor that plays key roles in extracellular calcium ion (Ca2+o) homeostasis in parathyroid gland and kidney. Macrophage-like mononuclear cells appear at sites of osteoclastic bone resorption during bone remodeling and may play a role in...
Topics
- Amino Acid Sequence
- Animals
- Calcium-Binding Proteins
- Cell Line
- Chemotaxis
- DNA
- Immunohistochemistry
- Macrophages
- Mice
- Molecular Sequence Data
- Monocytes
- Phenotype
- RNA, Messenger
- Reverse Transcriptase Polymerase Chain Reaction
