Article
Effect of Interleukin-6 promoter polymorphisms in survivors of myocardial infarction and matched controls in the North and South of Europe. The HIFMECH Study.
Thrombosis and haemostasis - 1 Nov 2004
Kelberman Daniel, Hawe E, Luong L A, Mohamed-Ali Vidya, Lundman Pia, Tornvall Per, Aillaud M F, Juhan-Vague Irène, Yudkin John S, Margaglione Maurizio, di Minno Giovanni, Tremoli Elena, Humphries Stephen E
Abstract excerpt
Elevated plasma IL-6 levels have been implicated in the pathogenesis of coronary heart disease. We have investigated the association of two polymorphisms in the promoter of IL-6 (-572G>C and -174G>C) with levels of inflammatory markers and risk of myocardial infarction (MI) in a European study of MI survivors and age-matched controls from two high-risk centres in the North of Europe, and two low risk centres in...
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