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Article

A basic peptide within the juxtamembrane region is required for EGF receptor dimerization.

Experimental cell research - 1 Jan 2005

Aifa Sami, Aydin Jan, Nordvall Gunnar, Lundström Ingemar, Svensson Samuel P S, Hermanson Ola

Abstract excerpt

The epidermal growth factor receptor (EGFR) is fundamental for normal cell growth and organ development, but has also been implicated in various pathologies, notably tumors of epithelial origin. We have previously shown that the initial 13 amino acids (P13) within the intracellular juxtamembrane region (R645-R657) are involved in the interaction with calmodulin, thus indicating an important role for this region...

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Source

Identifiers

PMID: 15541730
DOI: 10.1016/j.yexcr.2004.08.032

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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