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Article

Decreased bone formation and osteopenia in mice lacking alpha-calcitonin gene-related peptide.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Dec 2004

Schinke Thorsten, Liese Sarah, Priemel Matthias, Haberland Michael, Schilling Arndt F, Catala-Lehnen Philip, Blicharski Dagmar, Rueger Johannes M, Gagel Robert F, Emeson Ronald B, Amling Michael

Abstract excerpt

UNLABELLED: We recently described an unexpected high bone mass phenotype in mice lacking the Calca gene that encodes CT and alphaCGRP. Here we show that mice specifically lacking alphaCGRP expression display an osteopenia caused by a decreased bone formation. These results show that alphaCGRP is...

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Source

Identifiers

PMID: 15537449
DOI: 10.1359/JBMR.040915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15537449-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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