Article
The role of calcitonin and alpha-calcitonin gene-related peptide in bone formation.
Archives of biochemistry and biophysics - 15 May 2008
Huebner Antje K, Keller Johannes, Catala-Lehnen Philip, Perkovic Sandra, Streichert Thomas, Emeson Ronald B, Amling Michael, Schinke Thorsten
Abstract excerpt
The Calca gene encodes two polypeptides, calcitonin (CT) and alpha-calcitonin gene-related peptide (alpha-CGRP), generated through alternative splicing. While CT, a hormone mainly produced by thyroidal C cells, has been described as a major regulator of bone resorption, alpha-CGRP, a neuropeptide...
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