Article
Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo.
The Journal of cell biology - 16 Feb 2004
Dacquin Romain, Davey Rachel A, Laplace Catherine, Levasseur Régis, Morris Howard A, Goldring Steven R, Gebre-Medhin Samuel, Galson Deborah L, Zajac Jeffrey D, Karsenty Gérard
Abstract excerpt
Amylin is a member of the calcitonin family of hormones cosecreted with insulin by pancreatic beta cells. Cell culture assays suggest that amylin could affect bone formation and bone resorption, this latter function after its binding to the calcitonin receptor (CALCR). Here we show that Amylin in...
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