Article

Periostin deficiency attenuates kidney fibrosis in diabetic nephropathy via improving pancreatic β-cell dysfunction

2023-04-06

Abstract excerpt

Diabetic nephropathy (DN) is associated with kidney fibrosis. A previous study revealed that periostin (POSTN) contributes to kidney fibrosis. This study examined the role of POSTN in DN. The urinary concentrations of POSTN and TNC increased according to the severity of DN in human samples. Streptozotocin (STZ) was administered after unilateral nephrectomy (UNXSTZ) to induce DN in both wild-type and Postn -null mi...

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Literature Corpus work: 73b9e2c6-9ac0-52a7-b724-0c96c360b6f0
DOI: 10.21203/rs.3.rs-2738091/v1

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