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Article

Functional analysis of human microsomal epoxide hydrolase genetic variants.

Chemico-biological interactions - 20 Nov 2004

Hosagrahara Vinayak P, Rettie Allan E, Hassett Christopher, Omiecinski Curtis J

Abstract excerpt

Human microsomal epoxide hydrolase (EPHX1) is active in the metabolism of many potentially carcinogenic or otherwise genotoxic epoxides, such as those derived from the oxidation of polyaromatic hydrocarbons. EPHX1 is polymorphic and encodes allelic variation at least two amino acid positions, Y11...

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Source

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Identifiers

PMID: 15535985
DOI: 10.1016/j.cbi.2004.07.004
PMCID: PMC4091877

Genes

EPHX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15535985-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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