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Article

Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms.

The Journal of biological chemistry - 15 Sept 2000

Sandberg M, Hassett C, Adman E T, Meijer J, Omiecinski C J

Abstract excerpt

Human soluble epoxide hydrolase (sEH), an enzyme directing the functional disposition of a variety of endogenous and xenobiotic-derived chemical epoxides, was characterized at the genomic level for interindividual variation capable of impacting function. RNA was isolated from 25 human liver samples and used to generate full-length copies of soluble epoxide hydrolase cDNA. The resulting cDNAs were polymerase chain...

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PMID: 10862610
DOI: 10.1074/jbc.M001153200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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