Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants.

Human molecular genetics - 1 Mar 1994

Hassett C, Aicher L, Sidhu J S, Omiecinski C J

Abstract excerpt

Human microsomal epoxide hydrolase (mEH) is a biotransformation enzyme that metabolizes reactive epoxide intermediates to more water-soluble trans-dihydrodiol derivatives. We compared protein-coding sequences from six full-length human mEH DNA clones and assessed potential amino acid variation at seven positions. The prevalence of these variants was assessed in at least 37 unrelated individuals using polymerase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genotype

Share to Molecular Sequence Data

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 7516776
DOI: 10.1093/hmg/3.3.421
PMCID: PMC4868095

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants.PMID 7516776Read ↗

Epoxide hydrolase--polymorphism and role in toxicology.Semantic proximity Read ↗

Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms.Semantic proximity Read ↗

Human hepatic microsomal epoxide hydrolase: comparative analysis of polymorphic expression.Semantic proximity Read ↗

Meta-analysis of microsomal epoxide hydrolase gene polymorphism and risk of hepatocellular carcinoma.Semantic proximity Read ↗

Polymorphisms in human soluble epoxide hydrolase.Semantic proximity Read ↗

Functional analysis of human microsomal epoxide hydrolase genetic variants.Semantic proximity Read ↗

Non-synonymous single nucleotide alterations in the microsomal epoxide hydrolase gene and their functional effects.Semantic proximity Read ↗

Meta-analysis of microsomal epoxide hydrolase gene polymorphism and the risk of breast carcinoma.Semantic proximity Read ↗

Epoxide hydrolase genotype and orolaryngeal cancer risk: interaction with GSTM1 genotype.Semantic proximity Read ↗

Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer.Semantic proximity Read ↗

Microsomal epoxide hydrolase polymorphismsSemantic proximity Read ↗

Inhibition of human m-epoxide hydrolase gene expression in a case of hypercholanemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.