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Article

Epoxide hydrolase--polymorphism and role in toxicology.

Toxicology letters - 15 Mar 2000

Omiecinski C J, Hassett C, Hosagrahara V

Abstract excerpt

Microsomal epoxide hydrolase is a critical biotransformation enzyme that catalyzes the conversion of a broad array of xenobiotic epoxide substrates to more polar diol metabolites. The gene has been shown previously to exhibit polymorphism, including variation in the coding region leading to amino acid substitutions at positions 113 (Y/H) and 139 (H/R). To better evaluate the phenotype associated with the...

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Source

Identifiers

PMID: 10720753
DOI: 10.1016/s0378-4274(99)00235-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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