Article
Variability in the PR and RT genes of HIV-1 isolated from recently infected subjects.
Antiviral chemistry & chemotherapy - 1 Sept 2004
Turner Dan, Roldan Ariel, Brenner Bluma, Moisi Daniela, Routy Jean-Pierre, Wainberg Mark A
Abstract excerpt
To study variability in reverse transcriptase (RT) and protease (PR) genes of HIV-1 isolated from recently infected patients identified between 1997 and 2003, sequences were obtained on the RT and PR genes of viruses harvested from plasma of 121 non-treated subjects who had undergone primary HIV infection. The degree of dissimilarity between the viruses studied and a reference HIV-1 subtype B strain (LAV-1) was...
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