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Article

Consistent risk group-associated differences in human immunodeficiency virus type 1 vpr, vpu and V3 sequences despite independent evolution.

The Journal of general virology - 1 Apr 1996

Kuiken C L, Cornelissen M T, Zorgdrager F, Hartman S, Gibbs A J, Goudsmit J

Abstract excerpt

Human immunodeficiency virus 1 type vpr, vpu and V3 sequences from 15 homosexual men and 19 intravenous drug users in the Amsterdam Cohort studies were analysed. Previously, we reported that V3 domains of viruses from drug users are distinguishable from those of homosexual men on the basis of two silent mutations. Phylogenetic analysis of vpr, vpu and V3 shows that differences in all three regions correlate with...

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PMID: 8627267
DOI: 10.1099/0022-1317-77-4-783

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