Polymorphisms and resistance mutations in the protease and reverse transcriptase genes of HIV-1 F subtype Romanian strains.

doi:10.1016/j.ijid.2005.11.006

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Article

Polymorphisms and resistance mutations in the protease and reverse transcriptase genes of HIV-1 F subtype Romanian strains.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Mar 2007

Paraschiv Simona, Otelea Dan, Dinu Magdalena, Maxim Daniela, Tinischi Mihaela

Abstract excerpt

OBJECTIVE: To evaluate the prevalence of resistance mutations in the genome of HIV-1 F subtype strains isolated from Romanian antiretroviral (ARV) treatment-naïve patients and to assess the phylogenetic relatedness of these strains with other HIV-1 strains. METHODS: Twenty-nine HIV-1 strains isol...

Topics

Adolescent
Adult
Drug Resistance, Viral
Genotype
HIV Protease
HIV Protease Inhibitors
HIV Reverse Transcriptase
HIV-1
Humans
Mutation
Phylogeny
Polymorphism, Genetic
Romania
Sequence Alignment

Source

Open in PubMed

Identifiers

PMID: 16762582
DOI: 10.1016/j.ijid.2005.11.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-16762582-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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