Article
Polymorphisms and resistance mutations in the protease and reverse transcriptase genes of HIV-1 F subtype Romanian strains.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Mar 2007
Paraschiv Simona, Otelea Dan, Dinu Magdalena, Maxim Daniela, Tinischi Mihaela
Abstract excerpt
OBJECTIVE: To evaluate the prevalence of resistance mutations in the genome of HIV-1 F subtype strains isolated from Romanian antiretroviral (ARV) treatment-naïve patients and to assess the phylogenetic relatedness of these strains with other HIV-1 strains. METHODS: Twenty-nine HIV-1 strains isolated from treatment-naïve adolescents (n=15) and adults (n=14) were included in this study. Resistance genotyping was...
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