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Article

The role of polymorphisms of glutathione S-transferases GSTM1, M3, P1, T1 and A1 in susceptibility to alcoholic liver disease.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000

Brind A M, Hurlstone A, Edrisinghe D, Gilmore I, Fisher N, Pirmohamed M, Fryer A A

Abstract excerpt

AIMS AND METHODS: Oxidant stress is proposed to be an important pathogenic factor in liver damage related to alcohol. The glutathione S-transferases (GSTs) are a group of polymorphic enzymes that are important in protection against oxidant stress. As there is evidence for genetic susceptibility to alcohol-related liver disease we have compared the frequency of polymorphisms of GSTM1, M3, P1, T1 and A1 by...

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Source

Identifiers

PMID: 15525789
DOI: 10.1093/alcalc/agh105

Genes

GSTM1
GSTA1
GSTT1
GSTM3
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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