Article
Glutathione-S-transferase GST M1 "null" genotype and the risk of alcoholic liver disease.
Alcoholism, clinical and experimental research - 1 Nov 1996
Savolainen V T, Pjarinen J, Perola M, Penttilä A, Karhunen P J
Abstract excerpt
The present study was conducted to investigate possible association between the occurrence of glutathione-S-transferase GST M1 "null" genotype and alcoholic liver disease (ALD). The"null" genotype indicating absent activity of class mu glutathione transferase was assessed in 33 abstainers, 43 moderate alcohol consumers, and 313 heavy alcohol consumers by polymerase chain reaction. The genotypes were compared with...
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