Article
Glutathione-S-transferase GST M1 "null" genotype and the risk of alcoholic liver disease.
Alcoholism, clinical and experimental research - 1 Nov 1996
Savolainen V T, Pjarinen J, Perola M, Penttilä A, Karhunen P J
Abstract excerpt
The present study was conducted to investigate possible association between the occurrence of glutathione-S-transferase GST M1 "null" genotype and alcoholic liver disease (ALD). The"null" genotype indicating absent activity of class mu glutathione transferase was assessed in 33 abstainers, 43 mod...
Topics
- Adult
- Aged
- Alcoholism
- Chromosome Deletion
- Gene Frequency
- Genotype
- Glutathione Transferase
- Humans
- Liver
- Liver Cirrhosis, Alcoholic
- Liver Diseases, Alcoholic
- Male
- Middle Aged
- Models, Genetic
- Odds Ratio
- Polymerase Chain Reaction
- Risk Factors