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Article

Meta-analysis: glutathione-S-transferase allelic variants are associated with alcoholic liver disease.

Alimentary pharmacology & therapeutics - 1 Nov 2011

Marcos M, Pastor I, Chamorro A-J, Ciria-Abad S, González-Sarmiento R, Laso F-J

Abstract excerpt

BACKGROUND: Only a minority of alcoholics develop alcoholic liver disease (ALD) and allelic variants within genes encoding glutathione-S-transferases (GST) have been associated with ALD vulnerability with controversial results. AIM: To assess the effects of GST polymorphisms on ALD by means of a genetic association study and meta-analysis. METHODS: We retrieved published studies on the relationship between...

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Share to Alcoholism
Share to Alleles
Share to GSTP1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Glutathione Transferase

Share to Liver Diseases, Alcoholic

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 21967547
DOI: 10.1111/j.1365-2036.2011.04862.x

Genes

GSTM1
GSTP1
GSTT1

Provenance

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