Article
Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study.
Genetic epidemiology - 1 Apr 2009
Boyles Abee L, Wilcox Allen J, Taylor Jack A, Shi Min, Weinberg Clarice R, Meyer Klaus, Fredriksen Ase, Ueland Per Magne, Johansen Anne Marte W, Drevon Christian A, Jugessur Astanand, Trung Truc Nguyen, Gjessing Håkon K, Vollset Stein Emil, Murray Jeffrey C, Christensen Kaare, Lie Rolv T
Abstract excerpt
An increased risk of facial clefts has been observed among mothers with lower intake of folic acid or vitamin A around conception. We hypothesized that the risk of clefts may be further moderated by genes involved in metabolizing folate or vitamin A. We included 425 case-parent triads in which th...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.