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Article

Fetal and maternal MTHFR C677T genotype, maternal folate intake and the risk of nonsyndromic oral clefts.

American journal of medical genetics. Part A - 1 Feb 2007

Chevrier Cécile, Perret Claire, Bahuau Michel, Zhu Huiping, Nelva Agnès, Herman Christine, Francannet Christine, Robert-Gnansia Elisabeth, Finnell Richard H, Cordier Sylvaine

Abstract excerpt

The association between maternal folate intake and risk of nonsyndromic oral clefts has been studied among many populations with conflicting results. The methylenetetrahydrofolate reductase gene (MTHFR) plays a major role in folate metabolism, and several polymorphisms, including C677T, are common in European populations. Data from a French study (1998-2001) let us investigate the roles of maternal dietary folate...

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Source

Identifiers

PMID: 17219389
DOI: 10.1002/ajmg.a.31462

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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