Article
Comparative genetics of albinism.
Ophthalmic paediatrics and genetics - 1 Sept 1990
Searle A G
Abstract excerpt
Albinism in laboratory mammals is equivalent to human tyrosinase-negative oculocutaneous albinism, and thus the result of recessive mutation in the structural locus for tyrosinase (TYR), which prevents melanin biosynthesis. In the mouse, eight mutant alleles are now known at this locus, with diff...
Topics
- Albinism
- Albinism, Ocular
- Albinism, Oculocutaneous
- Alleles
- Animals
- Chromosome Deletion
- Eye Color
- Humans
- Melanins
- Melanocytes
- Monophenol Monooxygenase
- Mutation