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Article

Mice lacking the syndecan-3 gene are resistant to diet-induced obesity.

The Journal of clinical investigation - 1 Nov 2004

Strader April D, Reizes Ofer, Woods Stephen C, Benoit Stephen C, Seeley Randy J

Abstract excerpt

The accurate matching of caloric intake to caloric expenditure involves a complex system of peripheral signals and numerous CNS neurotransmitter systems. Syndecans are a family of membrane-bound heparan sulfate proteoglycans that modulate ligand-receptor interactions. Syndecan-3 is heavily expres...

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Identifiers

PMID: 15520868
DOI: 10.1172/JCI20631
PMCID: PMC524223

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15520868-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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