Article
Role of syndecan-3 polymorphisms in obesity and female hyperandrogenism.
Journal of molecular medicine (Berlin, Germany) - 1 Dec 2009
Schüring Andreas N, Lutz Friederike, Tüttelmann Frank, Gromoll Jörg, Kiesel Ludwig, Götte Martin
Abstract excerpt
The heparan sulfate proteoglycan syndecan-3 (SDC3) is a novel regulator of feeding behavior and body weight. Recently, an association of SDC3 polymorphisms with obesity has been observed in Koreans. As female obesity is associated with hyperandrogenism and infertility, we studied the role of SDC3 polymorphisms in female individuals undergoing diagnostics prior to infertility treatment. For this purpose, endocrine...
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