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Article

Increased body fat in mice with a targeted mutation of the paternally expressed imprinted gene Peg3.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2005

Curley J P, Pinnock S B, Dickson S L, Thresher R, Miyoshi N, Surani M A, Keverne E B

Abstract excerpt

Peg3 encodes a C2H2 type zinc finger protein that is implicated in a novel physiological pathway regulating core body temperature, feeding behavior, and obesity in mice. Peg3+/- mutant mice develop an excess of abdominal, subcutaneous, and intra-scapular fat, despite a lifetime of lower food inta...

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PMID: 15928196
DOI: 10.1096/fj.04-3216fje

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15928196-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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