Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complex patterns of transcription at the insertion site of a retrotransposon in the mouse.

Nucleic acids research - 1 Jan 2004

Druker Riki, Bruxner Timothy James, Lehrbach Nicolas John, Whitelaw Emma

Abstract excerpt

Here we report that transcriptional effects of the insertion of a retrotransposon can occur simultaneously both upstream and downstream of the insertion site. We have identified an intra-cisternal A particle (IAP) retrotransposon in intron 6 of a gene that we have named Cabp (CDK5 activator binding protein). The presence of the IAP is associated with an aberrant transcript initiating from a cryptic promoter in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Methylation
Share to Mice, Inbred C57BL
Share to Mutagenesis, Insertional

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polyadenylation

Share to Retroelements

Share to RNA, Messenger

Share to Terminal Repeat Sequences

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 15520464
DOI: 10.1093/nar/gkh914
PMCID: PMC528799

Genes

CDK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complex patterns of transcription at the insertion site of a retrotransposon in the mouse.PMID 15520464Read ↗

Retrotransposons influence the mouse transcriptome: implication for the divergence of genetic traits.Semantic proximity Read ↗

Retrotransposons as a major source of epigenetic variations in the mammalian genome.Semantic proximity Read ↗

Intracisternal A particle genes: Distribution in the mouse genome, active subtypes, and potential roles as species-specific mediators of susceptibility to cancer.Semantic proximity Read ↗

Identification of autonomous IAP LTR retrotransposons mobile in mammalian cells.Semantic proximity Read ↗

Sequence features of retrotransposons allow for epigenetic variabilitySemantic proximity Read ↗

Sequence features of retrotransposons allow for epigenetic variability.Semantic proximity Read ↗

Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus.Semantic proximity Read ↗

Genetically regulated epigenetic transcriptional activation of retrotransposon insertion confers mouse dactylaplasia phenotype.Semantic proximity Read ↗

Opposite orientations of an inverted duplication and allelic variation at the mouse agouti locus.Semantic proximity Read ↗

Identification of the functional elements in the bidirectional promoter of the mouse O-sialoglycoprotein endopeptidase and APEX nuclease genes.Semantic proximity Read ↗

Retrotransposition of limited deletion type of intracisternal A-particle elements in the myeloid leukemia Clls of C3H/He mice.Semantic proximity Read ↗

Int-6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.