Article
Retrotransposition of limited deletion type of intracisternal A-particle elements in the myeloid leukemia Clls of C3H/He mice.
Journal of radiation research - 1 Mar 2004
Ishihara Hiroshi, Tanaka Izumi, Wan Hong, Nojima Kumie, Yoshida Kazuko
Abstract excerpt
The murine genome has about 1,000 copies of DNA elements for the intracisternal A-particle (IAP) that resembles a retrovirus. We previously reported that the genomic DNA of the cells from radiation-induced acute myeloid leukemia (AML) lines derived from C3H/He inbred mice was frequently rearranged by the integration of the IAP element. In this study, 8 IAP elements from the characteristic integration sites in 6...
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