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Article

Genetically regulated epigenetic transcriptional activation of retrotransposon insertion confers mouse dactylaplasia phenotype.

Proceedings of the National Academy of Sciences of the United States of America - 27 Nov 2007

Kano Hiroki, Kurahashi Hiroki, Toda Tatsushi

Abstract excerpt

Dactylaplasia, characterized by missing central digital rays, is an inherited mouse limb malformation that depends on two genetic loci. The first locus, Dac, is an insertional mutation around the dactylin gene that is inherited as a semidominant trait. The second locus is an unlinked modifier, md...

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Identifiers

PMID: 17984064
DOI: 10.1073/pnas.0705483104
PMCID: PMC2141903

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17984064-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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