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Article

Identification of the functional elements in the bidirectional promoter of the mouse O-sialoglycoprotein endopeptidase and APEX nuclease genes.

Biochemical and biophysical research communications - 30 Aug 2002

Ikeda Shogo, Ayabe Hiroaki, Mori Kazuhisa, Seki Yuichi, Seki Shuji

Abstract excerpt

The gene for mammalian O-sialoglycoprotein endopeptidase (Osgep) lies immediately adjacent to the gene for the APEX nuclease (Apex), a multifunctional DNA repair enzyme, in a head-to-head orientation. To clarify the regulation of these divergent genes, we studied their promoter regions with luciferase reporters. Deletion analysis of a fragment containing the entire mouse Apex gene suggested that cis-acting...

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PMID: 12200116
DOI: 10.1016/s0006-291x(02)00939-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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