Article
Phenotypic heterogeneity in nucleotide excision repair mutants of rodent complementation groups 1 and 4.
Mutation research - 12 Mar 1997
Busch D B, van Vuuren H, de Wit J, Collins A, Zdzienicka M Z, Mitchell D L, Brookman K W, Stefanini M, Riboni R, Thompson L H, Albert R B, van Gool A J, Hoeijmakers J
Abstract excerpt
Rodent ultraviolet light (UV)-sensitive mutant cells in complementation groups (CGs) 1 and 4 normally are known for their extraordinary (approximately 80-100 x) sensitivity to mitomycin C (MMC), although some CG1 mutants with reduced MMC sensitivity were previously reported (Stefanini et al. (198...
Topics
- Acetoxyacetylaminofluorene
- Adenine
- Alleles
- Animals
- CHO Cells
- Cells, Cultured
- Cricetinae
- DNA
- DNA Repair
- DNA, Complementary
- DNA-Binding Proteins
- Endonucleases
- Ethyl Methanesulfonate
- Gamma Rays