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Article

ERCC1 mutations in UV-sensitive Chinese hamster ovary (CHO) cell lines.

Mutation research - 1 Jun 1998

Hayashi T, Takao M, Tanaka K, Yasui A

Abstract excerpt

In mammalian nucleotide excision repair (NER), the ERCC1 protein is known to act as a complex with ERCC4 (XPF) protein, which is necessary for stability of ERCC1, and this complex introduces an incision on the 5' side of a damaged site in DNA. ERCC1 also binds to XPA protein to make a large protein complex at the site of DNA damage. Since no human disease associated with ERCC1 has been identified, Chinese hamster...

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Source

Identifiers

PMID: 9653453
DOI: 10.1016/s0921-8777(98)00013-5

Genes

ERCC1
XPA
ERCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ERCC1 mutations in UV-sensitive Chinese hamster ovary (CHO) cell lines.PMID 9653453Read ↗

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Molecular cloning and biological characterization of the human excision repair gene ERCC-3.Semantic proximity Read ↗

Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair.Semantic proximity Read ↗

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