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Article

Defective tumor necrosis factor alpha-induced maturation of monocyte-derived dendritic cells in patients with myelodysplastic syndromes.

Clinical immunology (Orlando, Fla.) - 1 Dec 2004

Micheva Ilina, Thanopoulou Eleni, Michalopoulou Sotiria, Karakantza Marina, Kouraklis-Symeonidis Alexandra, Mouzaki Athanasia, Zoumbos Nicholas

Abstract excerpt

Myelodysplastic syndromes (MDS) are clonal stem cell disorders, characterized by ineffective and dysplastic hematopoiesis. MDS patients have a defective immune response manifested by increased susceptibility to bacterial infections, autoimmune phenomena, and high incidence of lymphoid malignancies. Presently, we investigated the phenotype and function of monocyte-derived dendritic cells (MoDC) in 23 MDS patients...

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PMID: 15507396
DOI: 10.1016/j.clim.2004.08.007

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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