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Article

Normal monocyte-derived dendritic cell function in patients with Langerhans-cell-histiocytosis.

Medical and pediatric oncology - 1 Sept 2002

Holter Wolfgang, Ressmann Gabriele, Grois Nicole, Lehner Manfred, Parolini Ornella, Gadner Helmut

Abstract excerpt

BACKGROUND: Langerhans cell histiocytosis (LCH) is a histiocytic disease, characterized by the lesional accumulation of dendritic Langerhans cells together with T cells and eosinophils. The cause of this disease is unknown. Langerhans cells are bone marrow-derived dendritic cells (DCs), which can develop from CD34(+) hematopoietic progenitor cells as well as from monocytes. PROCEDURE: To test whether LCH patients...

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Identifiers

PMID: 12210447
DOI: 10.1002/mpo.10129

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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