Article
Dendritic cells in chronic myelomonocytic leukaemia.
British journal of haematology - 1 Jun 1999
Vuckovic S, Fearnley D B, Gunningham S, Spearing R L, Patton W N, Hart D N
Abstract excerpt
Blood dendritic cells (DC) differentiate in vitro via two separate pathways: either directly from blood DC precursors (DCp) or from CD14+ monocytes. In chronic myelomonocytic leukaemia (CMML) abnormal bone marrow precursors contribute to blood monocyte development but DC development has not been studied previously. Monocytes comprised 60% of blood MNC in 15 CMML patients studied, compared with 20% in 16...
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