Article
Differentiation of Monocyte Derived Dendritic Cells in End Stage Renal Disease is Skewed Towards Accelerated Maturation.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jan 2000
Dopheide Joern F, Zeller Geraldine C, Kuhlmann Martin, Girndt Matthias, Sester Martina, Sester Urban
Abstract excerpt
BACKGROUND: Dendritic cells (DC) play an important role in the induction of immune responses. Patients with end stage renal disease (ESRD) suffer from chronic inflammation, leading to a secondary, uremic immunodeficiency associated with alterations in monocyte subpopulations with increased proinflammatory capacities. OBJECTIVES: The aim of this study was to examine, under isolated conditions, whether alterations...
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