Differentiation of Monocyte Derived Dendritic Cells in End Stage Renal Disease is Skewed Towards Accelerated Maturation.

doi:10.17219/acem/40463

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Article

Differentiation of Monocyte Derived Dendritic Cells in End Stage Renal Disease is Skewed Towards Accelerated Maturation.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jan 2000

Dopheide Joern F, Zeller Geraldine C, Kuhlmann Martin, Girndt Matthias, Sester Martina, Sester Urban

Abstract excerpt

BACKGROUND: Dendritic cells (DC) play an important role in the induction of immune responses. Patients with end stage renal disease (ESRD) suffer from chronic inflammation, leading to a secondary, uremic immunodeficiency associated with alterations in monocyte subpopulations with increased proinflammatory capacities. OBJECTIVES: The aim of this study was to examine, under isolated conditions, whether alterations...

Topics

Age Factors
Aged
Biomarkers
Case-Control Studies
Cell Differentiation
Cells, Cultured
Dendritic Cells
Female
GPI-Linked Proteins
Humans
Kidney Failure, Chronic
Lipopolysaccharide Receptors
Lipopolysaccharides

Source

Open in PubMed

Identifiers

PMID: 25931358
DOI: 10.17219/acem/40463

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Monocytes

Phenotype

Receptors, IgG