Article
Serum lamivudine levels in the presence of a lamivudine-resistant HBV mutant.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Oct 2004
Torre F, Mattioli F, Campo N, Delfino A, Basso M, Pelli N, Martelli A, Picciotto A
Abstract excerpt
BACKGROUND/AIMS: Lamivudine efficiently inhibits hepatitis B virus replication and has been used to treat hepatitis B virus recurrence after orthotopic liver transplantation. Although effective, its use is hampered by viral breakthrough due to the appearance of hepatitis B virus drug-resistant strains. Aims of this work were to evaluate the inter- and intra-individual variations of lamivudine serum levels and the...
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