Article
Transient emergence of hepatitis B variants in a patient with chronic hepatitis B resistant to lamivudine.
Journal of hepatology - 1 Mar 1998
Buti M, Jardi R, Cotrina M, Rodriguez-Frias F, Esteban R, Guardia J
Abstract excerpt
BACKGROUND: Lamivudine is a cytosine nucleoside analogue that inhibits hepatitis B virus replication. Resistance to lamivudine monotherapy has been reported in patients who received lamivudine to prevent recurrent hepatitis B virus infection after liver transplantation. No cases of resistance have been described in patients who did not clear HBV DNA during lamivudine therapy. METHODS: We report the case of an...
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