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Article

[Evolution of hepatitis B virus quasispecies during antiviral therapy in one chronic hepatitis B patient].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Jul 2011

Liang Pan-pan, Guo Jin-jun, Li Qing-ling, Luo Qiang, Shi Xiao-feng, Huang Ai-long

Abstract excerpt

OBJECTIVE: To investigate the evolution of hepatitis B virus (HBV) quasispecies in one patient during lamivudine (LAM) monotherapy and switching to entecavir (ETV) rescue treatment. METHODS: Serum samples were taken at seven different time points during antiviral therapy (0, 24, 48, 60, 72, 96, 152 weeks, respectively), the HBV DNA polymerase gene was amplified, cloned and sequenced to analyze the amino acid...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22152243
DOI: 10.3760/cma.j.issn.1007-3418.2011.07.012

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