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Article

Expression of PDE5 splice variants during ontogenesis of chick dorsal root ganglia.

Journal of neuroscience research - 15 Dec 2004

Giordano Daniela, Giorgi Mauro, Tata Ada Maria, Modica Anna, Augusti-Tocco Gabriella

Abstract excerpt

Cyclic GMP (cGMP)-binding cGMP-specific phosphodiesterase (PDE5) activity was found in chick dorsal root ganglia (DRG). PDE5 expression was studied at different stages of development: in embryonic day 10 (E10) and E18 embryos and in 5-day post-hatching chick (P5). The presence of PDE5 was suggested by the ion exchange chromatography elution profile in E18 DRG extracts, where cGMP-specific hydrolytic...

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Identifiers

PMID: 15505792
DOI: 10.1002/jnr.20337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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