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Article

Striatum- and testis-specific phosphodiesterase PDE10A isolation and characterization of a rat PDE10A.

European journal of biochemistry - 1 Dec 1999

Fujishige K, Kotera J, Omori K

Abstract excerpt

PDE10A, a phosphodiesterase (PDE) exhibiting properties of a cAMP PDE and a cAMP-inhibited cGMP PDE, was cloned and investigated in detail in rats. PDE10A transcripts were abundant in the brain and testis. In situ hybridization analysis using a PDE10A riboprobe demonstrated the presence of PDE10A transcripts in the neurons of the striatum and the olfactory tubercle regions of the brain. Rat PDE10A cDNAs were...

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PMID: 10583409
DOI: 10.1046/j.1432-1327.1999.00963.x

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