Article
Identification and tissue-specific expression of PDE7 phosphodiesterase splice variants.
Proceedings of the National Academy of Sciences of the United States of America - 26 Nov 1996
Bloom T J, Beavo J A
Abstract excerpt
Type 7 cyclic nucleotide phosphodiesterases (PDE7s) are a newly described family of enzymes having high affinity and specificity for cAMP. However, little is known about their structure, function, or regulation. We have isolated a mouse skeletal muscle cDNA representing a new alternative splice v...
Topics
- Alternative Splicing
- Animals
- B-Lymphocytes
- Base Sequence
- Cell Line
- Chromatography, High Pressure Liquid
- Cloning, Molecular
- Gene Library
- Genetic Variation
- Humans
- Mice
- Molecular Sequence Data
- Molecular Weight
- Muscle, Skeletal
- Open Reading Frames
- Organ Specificity
- Phosphoric Diester Hydrolases
- T-Lymphocytes