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Article

Identification and tissue-specific expression of PDE7 phosphodiesterase splice variants.

Proceedings of the National Academy of Sciences of the United States of America - 26 Nov 1996

Bloom T J, Beavo J A

Abstract excerpt

Type 7 cyclic nucleotide phosphodiesterases (PDE7s) are a newly described family of enzymes having high affinity and specificity for cAMP. However, little is known about their structure, function, or regulation. We have isolated a mouse skeletal muscle cDNA representing a new alternative splice variant (PDE7A2) of the PDE7 gene. The ORF encodes a 456-amino acid protein having a predicted molecular weight of 52.4...

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Identifiers

PMID: 8943082
DOI: 10.1073/pnas.93.24.14188
PMCID: PMC19515

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Source receipt: pubmed, retrieved 7 Sept 2026.

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