Article
Variation in NCB5OR: studies of relationships to type 2 diabetes, maturity-onset diabetes of the young, and gestational diabetes mellitus.
Diabetes - 1 Nov 2004
Andersen Gitte, Wegner Lise, Rose Christian Schack, Xie Jianxin, Zhu Hao, Larade Kevin, Johansen Anders, Ek Jakob, Lauenborg Jeannet, Drivsholm Thomas, Borch-Johnsen Knut, Damm Peter, Hansen Torben, Bunn H Franklin, Pedersen Oluf
Abstract excerpt
Recent data show that homozygous Ncb5or(-/-) knock-out mice present with an early-onset nonautoimmune diabetes phenotype. Furthermore, genome-wide scans have reported linkage to the chromosome 6q14.2 region close to the human NCB5OR. We therefore considered NCB5OR to be a biological and positional candidate gene and examined the coding region of NCB5OR in 120 type 2 diabetic patients and 63 patients with...
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