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Article

A novel single nucleotide polymorphism (SNP) of the CYP2C19 gene in a Japanese subject with lowered capacity of mephobarbital 4'-hydroxylation.

Drug metabolism and pharmacokinetics - 1 Jun 2004

Morita Jun, Kobayashi Kaoru, Wanibuchi Atsuko, Kimura Miyuki, Irie Shin, Ishizaki Takashi, Chiba Kan

Abstract excerpt

We sequenced all nine exons and exon-intron junctions of the cytochrome P450 2C19 (CYP2C19) gene from a Japanese subject with a lowered capacity of CYP2C19-mediated 4'-hydroxylation after an oral administration of mephobarbital. We found a novel single nucleotide polymorphism (SNP) of CYP2C19 gen...

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Identifiers

PMID: 15499191
DOI: 10.2133/dmpk.19.236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15499191-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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