Article
A rapid and simple detection of genetic defects responsible for the phenotypic polymorphism of cytochrome P450 2C19.
Biological & pharmaceutical bulletin - 1 Jan 1999
Itoh K, Inoue K, Yanagiwara S, Kyoya H, Suzuki T
Abstract excerpt
A rapid and simple cytochrome P450 (CYP) 2C19 genotyping system was established by making several modifications in previously reported procedures. PCR conditions were modified to be capable of simultaneous amplification of CYP2C19m1 and CYP2C19m2 regions. Intensive bands of 169 bp for the CYP2C19...
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