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Article

RseP (YaeL), an Escherichia coli RIP protease, cleaves transmembrane sequences.

The EMBO journal - 10 Nov 2004

Akiyama Yoshinori, Kanehara Kazue, Ito Koreaki

Abstract excerpt

Escherichia coli RseP (formerly YaeL) is believed to function as a 'regulated intramembrane proteolysis' (RIP) protease that introduces the second cleavage into anti-sigma(E) protein RseA at a position within or close to the transmembrane segment. However, neither its enzymatic activity nor the substrate cleavage position has been established. Here, we show that RseP-dependent cleavage indeed occurs within...

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Identifiers

PMID: 15496982
DOI: 10.1038/sj.emboj.7600449
PMCID: PMC526465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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