Article
Function of site-2 proteases in bacteria and bacterial pathogens.
Biochimica et biophysica acta - 1 Dec 2013
Schneider Jessica S, Glickman Michael S
Abstract excerpt
Site-2 proteases (S2Ps) are a class of intramembrane metalloproteases named after the founding member of this protein family, human S2P, which control cholesterol and fatty acid biosynthesis by cleaving Sterol Regulatory Element Binding Proteins which control cholesterol and fatty acid biosynthesis. S2Ps are widely distributed in bacteria and participate in diverse pathways that control such diverse functions as...
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