Article
A pair of circularly permutated PDZ domains control RseP, the S2P family intramembrane protease of Escherichia coli.
The Journal of biological chemistry - 12 Dec 2008
Inaba Kenji, Suzuki Mamoru, Maegawa Ken-ichi, Akiyama Shuji, Ito Koreaki, Akiyama Yoshinori
Abstract excerpt
The sigma(E) pathway of extracytoplasmic stress responses in Escherichia coli is activated through sequential cleavages of the anti-sigma(E) protein, RseA, by membrane proteases DegS and RseP. Without the first cleavage by DegS, RseP is unable to cleave full-length RseA. We previously showed that...
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