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Article

Wiskott–Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cells

19 Oct 2004

Abstract excerpt

The regulated migration and spatial localization of dendritic cells in response to environmental signals are critical events during the initiation of physiological immune responses and maintenance of tolerance. Cells deficient in the Wiskott-Aldrich syndrome protein (WASP) have been used to demonstrate the importance of the dynamic remodelling of the actin-based cytoskeleton during the selective adhesion and...

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Identifiers

PMID: 15495215
DOI: 10.1002/path.1651

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