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Wiskott‐Aldrich syndrome protein: Emerging mechanisms in immunity

14 Aug 2017

Abstract excerpt

The Wiskott-Aldrich syndrome protein (WASP) participates in innate and adaptive immunity through regulation of actin cytoskeleton-dependent cellular processes, including immune synapse formation, cell signaling, migration and cytokine release. There is also emerging evidence for a direct role in nuclear transcription programmes uncoupled from actin polymerization. A deeper understanding of some of the more...

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PMID: 28805251
DOI: 10.1002/eji.201646715

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