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Article

A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Apr 2006

Olivier Aurelie, Jeanson-Leh Laurence, Bouma Gerben, Compagno Daniel, Blondeau Johanna, Seye Khalil, Charrier Sabine, Burns Siobhan, Thrasher Adrian J, Danos Olivier, Vainchenker William, Galy Anne

Abstract excerpt

The Wiskott Aldrich syndrome protein (WASP) is a hematopoietic-specific cytoskeletal regulator that is necessary for induction of normal immunity. In the context of effective gene therapy for WAS, cellular models of human WASP deficiency are important for definition of the threshold of protein ex...

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Identifiers

PMID: 16360341
DOI: 10.1016/j.ymthe.2005.11.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16360341-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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