Article
Genome-scale models of microbial cells: evaluating the consequences of constraints.
Nature reviews. Microbiology - 1 Nov 2004
Price Nathan D, Reed Jennifer L, Palsson Bernhard Ø
Abstract excerpt
Microbial cells operate under governing constraints that limit their range of possible functions. With the availability of annotated genome sequences, it has become possible to reconstruct genome-scale biochemical reaction networks for microorganisms. The imposition of governing constraints on a reconstructed biochemical network leads to the definition of achievable cellular functions. In recent years, a...
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