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Article

Genome-scale metabolic network models for industrial microorganisms metabolic engineering: Current advances and future prospects.

Biotechnology advances - 1 Jan 2000

Gong Zhijin, Chen Jiayao, Jiao Xinyu, Gong Hao, Pan Danzi, Liu Lingli, Zhang Yang, Tan Tianwei

Abstract excerpt

The construction of high-performance microbial cell factories (MCFs) is the centerpiece of biomanufacturing. However, the complex metabolic regulatory network of microorganisms poses great challenges for the efficient design and construction of MCFs. The genome-scale metabolic network models (GSMs) can systematically simulate the metabolic regulation process of microorganisms in silico, providing effective...

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PMID: 38280495
DOI: 10.1016/j.biotechadv.2024.108319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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